To open the DC Power Flow Loss Setup dialog, select Simulator Options from the Case Options ribbon group on the Options ribbon tab. On the Power Flow Solution page, click on the tab labeled DC Options. Next, click the button labeled DC Loss Setup. This button will only be enabled when you check the box to Use DC Approximation in Power Flow/OPF/SCOPF.
The DC Power Flow Loss Setup dialog gives you a location to apply approximate losses during a DC load flow solution. The losses can be approximated by scaling the loads in the case to include an approximation of losses. Loss multiplication factors can be applied individually by bus, or as a group by area or by zone. Note that loss multipliers by area or by zone are just quick ways for setting the bus multiplication factors for all buses in the group. You will see the value reflected for all buses in the Buses page. If you wish to apply the same multiplication factor to the entire case, you can simply set the Case DC Loss Multiplier at the bottom of the dialog. This will automatically set all buses in the case to have the same DC Loss Multiplier specified.
Once the DC Loss Multipliers have been set, click OK to save the multipliers.